Prolotherapy for Knee Osteoarthritis: Benefits, Procedure, and Who Can Benefit
Knee osteoarthritis (OA) is one of the most common causes of pain, stiffness, and disability among adults. As the protective cartilage in the knee gradually wears away, patients often experience pain while walking, climbing stairs, sitting for prolonged periods, or even during sleep. While pain medications, physiotherapy, weight reduction, and injections can provide relief, many patients continue to experience persistent symptoms. In recent years, prolotherapy has emerged as a promising regenerative treatment option for selected patients with knee osteoarthritis. What Is Prolotherapy? Prolotherapy, short for "proliferation therapy," is a regenerative injection treatment that involves injecting a natural irritant solution—most commonly hypertonic dextrose (concentrated sugar solution)—into painful ligaments, tendons, and joint structures. The goal is to stimulate the body's natural healing response, strengthen weakened tissues, and improve joint stability. Unlike steroid...